Rx

Compounded Semaglutide + B12

From $159/moon the 6-month planSame price at every dose

  • One medication.

  • One weekly injection.

  • A real clinical plan behind it.

  • Compounded medications are not approved by the FDA. The FDA does not review compounded drugs for safety, effectiveness or quality. Compounded medications are prescribed only when a licensed provider determines they are appropriate for an individual patient. Compounded semaglutide is prepared by a licensed compounding pharmacy and requires a valid prescription from a licensed healthcare provider. Individual results vary. Not all patients will be eligible for treatment. This medication is not appropriate for every individual. Speak with your provider about the risks and benefits specific to your health history.

  • If you experience symptoms of a serious allergic reaction, pancreatitis, or vision changes, contact a healthcare provider immediately or call 911.

GLP-1 medications are prescription-only. A licensed healthcare provider must review your health intake assessment before any prescription is issued. Prescription issuance is not guaranteed and is solely at the discretion of the reviewing provider based on your individual health history and clinical criteria.

Choose your plan

Same price at every dose. All prices are all-in: medication, provider care, shipping and messaging are included.

What You Get with One Reserve

Prescription-based weight loss care, reviewed by a licensed medical provider.

  • Health assessment reviewed by a licensed provider

  • Prescription — where clinically appropriate

  • Medication compounded and shipped by a licensed pharmacy

  • Ongoing provider check-ins and dose adjustments

  • Access to your care team through the secure patient portal

The Science

What Semaglutide Does in Your Body

Semaglutide is a GLP-1 receptor agonist. GLP-1 is a hormone your gut produces naturally after eating — it signals your brain that you’ve had enough, slows digestion, and helps regulate blood sugar. Semaglutide works by mimicking that signal.

The result: reduced appetite, smaller portions feeling satisfying, and fewer of the constant hunger cues that make sustained weight loss so difficult for most people.

It’s not a willpower replacement. It’s a clinical tool that works with your biology — not around it.

Administered as a weekly subcutaneous (under-the-skin) injection. Your provider starts you at a low dose and adjusts upward based on your response and tolerability.

  • Complete your health assessment. Answer focused questions about your health history, current weight, and goals online. Takes about ten minutes.
  • A licensed provider reviews your intake and determines whether compounded semaglutide is clinically appropriate for you. Not a rubber stamp — a real clinical review.
  • If eligible, your provider issues a prescription. It is dispensed by a licensed compounding pharmacy.
  • Your medication arrives discreetly packaged at the address on your account. Your provider monitors your progress and adjusts dosing over time.

Compounded medications are not approved by the FDA. The FDA does not review compounded drugs for safety, effectiveness or quality. Compounded medications are prescribed only when a licensed provider determines they are appropriate for an individual patient. Compounded semaglutide and tirzepatide are prepared by state-licensed 503A or 503B compounding pharmacies. Results may vary. Individual results are not guaranteed.

Questions People Actually Ask

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One Life. One Body. Reserve It.

The future of health is here. You either act on it or you don’t. One Reserve is for people who act.

Prescription issuance is not guaranteed and is solely at the discretion of the reviewing provider.